4.7/5 • Rated by 1,632 Real Customers

Soften the Look of Fine Lines and Help Fade the Look of Dark Spots at Home

check_circle Helps reduce the appearance of fine lines and smooths skin texture, while helping infuse Lactose Exosomes beneath the skin’s surface

check_circle Painless and clinically shown to improve the look of firmness and texture in 8 weeks

check_circle Developed by bioengineers and dermatologists with 20+ years of experience

Choose Your Serum

Customer avatar (Verified reviewer)
Customer avatar
Customer avatar
50+ Board Certified Dermatologists
recommend Helenor ExoPlus to their patients.
  • 30-Day Money Back
  • Free Shipping Over $60
  • Backed by Science

A blend of 5 bio-engineered growth factor peptides mimics your skin’s repair messengers, encouraging faster cell renewal without the use of human-derived ingredients.

icon
Natural Repair Signals
Without spicules, exosomes can't get in. Our formula opens pathways first, then delivers messengers beneath the surface—triggering regeneration naturally.
icon
Visibly Lifts & Firms
Stimulates collagen production for tighter, more resilient skin, improved clarity & tone—and lasting results that build over time.
icon
2-in-1 Formula Outperforms Exosomes Alone:
Spicules create micro-channels so exosomes penetrate deeper—not just sit on the surface.
icon
Painless Barrier Repair & Strengthening
No clinic visits, no downtime. Strengthens and repairs from within.

Clinically proven to visibly improve the look of aging skin, ExoPlus® Serum features 5 bio-engineered peptides. This biotech-powered formula helps enhance the appearance of firmness, smooth texture, and reveal a more youthful-looking complexion.

The Clean Protocol:

  • Lacto Exosome — Probiotic-derived cellular messengers that accelerate skin renewal
  • Hydrolyzed Sponge (Spicules) — Marine micro-structures for deeper ingredient penetration
  • AHA + BHA + PHA — Triple acid blend that smooths texture and brightens
  • Niacinamide — Minimizes pores and evens skin tone
  • Panthenol — Deep hydration and barrier repair

Natural & safe
Cruelty free 
Sulfate free
Paraben free

The strength is tailored to your needs. Mild (2000 PPM) is perfect for daily care and maintenance. Strong (7500 PPM) delivers intense, deep renewal when used 2-3 times a week. Together, they create the ultimate skin transformation.

PPM = parts per million, referring to spicule concentration. Higher PPM means more micro-channels for deeper penetration and faster results.

icon
Mild
Daily use for sensitive skin
icon
Strong
For resilient wrinkles and texture
icon
Together
Significantly better skin

Use the Mild daily for consistent care and hydration. Incorporate the Strong 2-3 times a week for deeper, more intensive results. Together, they create a balanced routine for maximum impact

Gentle Icon
Gentle
Use Mild daily on delicate or sensitive skin
Intensive Icon
Intensive
Ideal for resilient skin; use Strong twice a week
Maximum Icon
Maximum
For transformative results; use 3 times a week

Jump to..

south How It Works south The Results south Reviews
south How To Use south FAQs
Helenor ExoPlus® Serum

Helenor ExoPlus® Serum

 4.7 • 1632 reviews
$39.00
$39.00 $59.70
SAVE 34% Sold out
View full details

Results you'll see with your own eyes

    AS SEEN IN

    “Few beauty trends are actually worth adopting, but Helenor's take on under skin Exosome-Infusion is a viral skin trend with merit.”

    So what are exosomes ?

    Exosomes are microscopic, bubble-like structures your body already produces. They function as tiny messengers, carrying proteins, RNA, and other bioactive molecules between cells. In skincare, they help promote tissue regeneration, reduce inflammation, and boost collagen production—making them a powerhouse for anti-aging treatments.

    At 25, your skin repairs itself. At 45, it needs help. Exosome production declines with age—ExoPlus puts it back.

    Unlike stem cells, exosomes signal your skin to repair itself. Ours are packed with extra peptides, growth factors, and antioxidants. And unlike other serums, spicules deliver them beneath the surface—not just on top.

    • Marine spicules

      Natural micro-needles from freshwater sponges. They create micro-channels in skin for deeper ingredient penetration.

    • Lacto Exosomes

      Probiotic messengers from Lactobacillus. They signal your cells to regenerate and renew faster than traditional serums.

    • The Powerful Combo

      Spicules open pathways. Exosomes deliver the payload. Micro-needling results without micro-needles.

      How are exosomes used in other treatments?

      stethoscope
      Clinic treatments

      A clinician punctures the skin with tiny pins, then exosomes are applied topically to absorb through the channels.

      rainy_light
      Laser treatments

      A laser machine burns off the outer skin layer. Afterward, exosomes are applied to speed healing on the raw surface.

      network_ping
      RF treatments

      RF device delivers radiofrequency heat deep into skin, then exosomes are applied to penetrate the open wounds.

      Helenor's ExoPlus goes where others can't

      Natural marine-spicules from freshwater sponges create micro-channels that stimulate collagen production while opening pathways for exosome delivery—improving the feel of firmness, smoothing texture, and reducing the look of fine lines and wrinkles.

      Lactobacillus-derived exosomes—nano-sized vesicles harvested from probiotic fermentation—carry bioactive peptides and signaling molecules that communicate directly with skin cells, triggering accelerated regeneration and repair at the cellular level. Spicules open pathways, exosomes deliver the payload—peptides, amino acids, and growth factors that signal cells to renew, repair, and produce collagen.

      What happens with consistent use of ExoPlus?

      1. acupuncture

        Day 01

        Spicule Activation

        Our proprietary formula uses advanced spicules—hydrolyzed marine sponge—to deliver exosomes directly into the dermis. These natural, marine-based micro-carriers penetrate the skin barrier, transporting bioactive exosomes deep beneath the surface to initiate cellular regeneration from within.

      2. face_shake

        Day 07

        First Signs

        Skin begins to feel different. Texture appears smoother to the touch, hydration levels improve, and a subtle glow starts to emerge. These early signals indicate that cellular renewal is underway beneath the surface.

      3. heart_smile

        Day 30

        Visible Renewal

        Real change becomes visible. Fine lines begin to soften, skin tone appears more even, and firmness starts to return. New collagen fibers are strengthening the dermal structure—this is regeneration you can see in the mirror.

      4. cheer

        Day 60

        Structural Transformation

        The full picture emerges. Wrinkles appear visibly reduced, elasticity is restored, and skin density feels firmer to the touch. Skin that has been rebuilt from the inside out—revealing a face that looks and behaves younger at a cellular level.
       
       

      Oh, and we did the Science

       

      Dr. Alaric Thorne, MD, PhD

      "We developed Helenor ExoPlus to deliver what clinic treatments can't—penetration and precision delivery. Traditional micro-procedures create channels but send nothing into them. Our marine-derived spicules open micro-channels while Lacto Exosomes flood them with peptides, amino acids, and growth factors, accelerating cellular renewal at a rate we hadn't seen with traditional serums. This is the first non-invasive treatment we've formulated that delivers measurable skin regeneration—without downtime or discomfort."

      Dr. Elara Holbrook, Board-Certified Dermatologist

      "We formulated ExoPlus to solve what frustrated me most about at-home skincare—nothing actually penetrated. Marine spicules changed that. Paired with Lacto Exosomes carrying peptides and growth factors, we finally achieved measurable cellular renewal outside the clinic. After years of development, this is the formula I stand behind."

      Dr. Julian Vance, DPT, Bioengineer

      "The science behind ExoPlus is what convinced me to join the development team. Marine spicules for penetration, yes—but the real innovation is what we're delivering: probiotic-derived exosomes loaded with peptides, amino acids, and growth factors. These aren't passive ingredients. They actively signal cells to turn over, rebuild, tighten. I've seen patients achieve in weeks what used to take months of clinical treatments."

      Dr. Sianna Holbrook, MD, Dermatologist

      "For more than ten years, my work focused on wrinkle repair research and cell aging reversal. Before we developed the formula, wrinkle repair failed for a simple reason: treatments created pathways, but delivered no intelligence. Channels without signals couldn't regenerate skin... They irritated it. ExoPlus solved that gap. Marine spicules open the channels with precision, and lacto-derived exosomes enter with active peptides, amino acids, and growth factors. The skin doesn’t guess what to do next, it’s instructed. When we merged delivery and signaling in ExoPlus, weeks replaced months. Wrinkle repair is not cosmetic, it is biological."

      •

      “Exosomes: your skin's very own power plant.”

      •

      Research shows 'powerful and measurable' effects in stimulating collagen production.

      •

      “Anti-aging science is littered with promising results [...] but ExoPlus seems different.”

      •

      “Exosome technology may hold key to reversing visible skin aging.”

      •

      “Exosomes: your skin's very own power plant.”

      •

      Research shows 'powerful and measurable' effects in stimulating collagen production.

      •

      “Anti-aging science is littered with promising results [...] but ExoPlus seems different.”

      •

      “Exosome technology may hold key to reversing visible skin aging.”

      •

      “Exosomes: your skin's very own power plant.”

      •

      Research shows 'powerful and measurable' effects in stimulating collagen production.

      •

      “Anti-aging science is littered with promising results [...] but ExoPlus seems different.”

      •

      “Exosome technology may hold key to reversing visible skin aging.”

      •

      “Exosomes: your skin's very own power plant.”

      •

      Research shows 'powerful and measurable' effects in stimulating collagen production.

      •

      “Anti-aging science is littered with promising results [...] but ExoPlus seems different.”

      •

      “Exosome technology may hold key to reversing visible skin aging.”

      In a Clinical Study of 133 Participants

      0%

      93%

      noticed results after their first week of ExoPlus treatment.

      0%

      89%

      of participants say their fine lines looked smoother.

      0%

      87%

      of participants say their skin looked brighter and more even toned.

      Conducted by a Non-Biased, 3rd Party Lab

      Helenor ExoPlus® Serum

      Helenor ExoPlus® Serum

      Mild & Strong Duo

      Loved By Tens of Thousands

        How to use your ExoPlus Serum

        1. Prepare

        Cleanse to begin.

        Start with a clean canvas. Gently cleanse your face to remove makeup, oil, and impurities. Pat dry. This ensures the spicules can penetrate effectively.

        Helenor®

        2. Apply

        Feel the tingle.

        Apply to key areas—under eyes, smile lines, forehead, cheeks, neck. Massage in using light upward strokes for 2-3 minutes. A slight tingle means it's working.

        Helenor®

        3. Seal & activate

        Renewal within.

        Seal with a water-based moisturizer like our Collagen Jelly Cream. Exosomes continue working beneath the surface for the next 24 hours.

        Helenor®

        4. Lasting results

        Consistency wins.

        Use ExoPlus daily (Mild). And Strong 2-3 times a week. Watch your skin transform—firmer, smoother, visibly renewed from within.

        Helenor®

        1. Prepare

        Cleanse to begin.

        Start with a clean canvas. Gently cleanse your face to remove makeup, oil, and impurities. Pat dry. This ensures the spicules can penetrate effectively.

        Helenor®

        2. Apply

        Feel the tingle.

        Apply to key areas—under eyes, smile lines, forehead, cheeks, neck. Massage in using light upward strokes for 2-3 minutes. A slight tingle means it's working.

        Helenor®

        3. Seal & activate

        Renewal within.

        Seal with a water-based moisturizer like our Collagen Jelly Cream. Exosomes continue working beneath the surface for the next 24 hours.

        Helenor®

        4. Lasting results

        Consistency wins.

        Use ExoPlus daily (Mild). And Strong 2-3 times a week. Watch your skin transform—firmer, smoother, visibly renewed from within.

        Helenor®

        1. Prepare

        Cleanse to begin.

        Start with a clean canvas. Gently cleanse your face to remove makeup, oil, and impurities. Pat dry. This ensures the spicules can penetrate effectively.

        Helenor®

        2. Apply

        Feel the tingle.

        Apply to key areas—under eyes, smile lines, forehead, cheeks, neck. Massage in using light upward strokes for 2-3 minutes. A slight tingle means it's working.

        Helenor®

        3. Seal & activate

        Renewal within.

        Seal with a water-based moisturizer like our Collagen Jelly Cream. Exosomes continue working beneath the surface for the next 24 hours.

        Helenor®

        4. Lasting results

        Consistency wins.

        Use ExoPlus daily (Mild). And Strong 2-3 times a week. Watch your skin transform—firmer, smoother, visibly renewed from within.

        Helenor®

        4.7 • 1634 Reviews

        Get more than a clinic level treatment everyday

        Buy Now & Save 53%

        Marine-derived spicules

        Lacto Exosomes

        Below surface repair

        All skin types

        Under $1/day

        Helenor ExoPlus®

        Other Serums

        Some

        Clinic Procedure

        Some

        $300/visit

        Join  millions  of people transforming their skin from within

         Reviewed on Trustpilot 09/2025

        My skin returned to life!

        "I purchased the strong serum from helenor exosome (7500) to deal with fine lines, wrinkles, and pigmentation. I also had mild sagging before, so was worried it could make it worse. However I’m so impressed with the initial results 3 treatments in. My skin RETURNED to LIFE!! I will not stop using this for a treatment that you would spend $300 in the clinic for just one invasive micro-needling session.. How amazing is it to be able to do it at home, and get way better results?”

        Customer avatar
        Ellie J., 57
        Treatment Phase: Week 3
         Reviewed on Trustpilot 12/2025

        Looking better and better

        “I’ve done two treatments so far since I got this and knew instantly. Wow. I have an extreme loss of redness and change in my bumpy skin! The best way to describe it is my skin feels settled, tight, and more even. I can't believe I finally got my real skin color back! Exosome is making the red undertone fade very fast!"

        Customer avatar
        Samantha L., 39
        Day 6 of 30 — Ongoing Treatment
         Reviewed on Trustpilot 01/2026

        Finally seeing progress with exosome after months of P.I.E.

        I've been dealing with post-inflammatory erythema for months after a bad breakout cycle. Stuff I used kept failing. Now I started using the Helenor Exosome a week ago and the change has honestly shocked me. I wanted to come on here and share this feedback. By day 2, my skin started calming down, and I haven’t had any new breakout in the past 5 days. My redness is dramatically reduced, my acne feels like it’s been pushed under the skin, and my complexion looks clearer and healthier overall. Thank you very much, Helenor. Exosome saved me!!

        Customer avatar
        Mia S., 28
        Week 1 – Skin Update
         
         

        Got Questions? We Got Answers!

        Our team is available 7 days a week to assist you with every possible worry - just email us at hey@helenor.com & we will be more than happy to help you!

        This next-gen serum fusesexosome-coated spiculeswith potent actives for deep renewal. Each spicule delivers exosomes loaded with peptides, amino acids, glutathione, and vitamins. AHA, BHA, and PHA smooth and brighten, while niacinamide boosts barrier function, and panthenol soothes and hydrates.The result? Fresh, healthy glow that starts from within.

        Absolutely! helenor™ ExoPlus is safe for sensitive skin. Made with gentle, skin-loving ingredients and free from harsh chemicals, it's perfect for all skin types. Start with a thin layer to tailor your routine. Carefully designed to tighten and smooth without causing any irritation.

        Definitely! helenor exosome is formulated to complement your existing skincare routine seamlessly. Whether you’re using serums, moisturizers, or sunscreen, or any other; our product works harmoniously to enhance your skin’s health and glow. For the ultimate boost against fine lines, pair it with our Korean Bio-Collagen Mask. Apply the exosome first to prep and nourish your skin, then follow with the mask to lock in hydration and maximize your glow. Your skin will thank you!

        • Water
        • Dipropylene Glycol
        • Glycerin
        • Butylene Glycol
        • 1,2-Hexanediol
        • Niacinamide
        • Sodium Polyacrylate
        • Ethylhexyl Palmitate
        • C12-14 Alketh-12
        • Polyglyceryl-10 Stearate
        • Polyglyceryl-10 Myristate
        • Hydrolyzed Sponge (Spicule)
        • Exosome
        • AHA (Alpha Hydroxy Acid)
        • BHA (Beta Hydroxy Acid)
        • PHA (Polyhydroxy Acid)

        1. Prep & Perfect – Cleanse and gently pat your face dry. Your skin is ready to soak in the magic.
        2. Glow Drop Moment – Apply helenor™ Exosome Shot to areas needing extra care—pores, fine lines, or uneven texture. Press and massage it in.
        3. Feel the Tingle, See the Magic – That tingle? It’s the active ingredients boosting elasticity, refining pores, and smoothing your skin.
        4. Seal & Reveal – Follow with a water-based moisturizer or helenor™ Bio-Collagen Mask to lock in hydration and nutrients.
        5. Your Skin, But Better – If you’re new to spicules, start slow with every other day use, then build up to daily for a healthy glow.

        Note: Avoid the eyes and lips. For sensitive skin, patch test first. Tingling, redness, or heat may occur, which may last for some time — don't worry, this is a natural reaction.

        Choose Your Strength: Exosome Shot 2000 – Mild, gentle care for smoother texture and refined pores. Perfect for beginners or sensitive skin. Exosome Shot 7500 – Strong, intensive care for visible renewal, pore tightening, and skin revitalization. For experienced users seeking maximum results.Pro Tip: Start with 2000 to prep your skin, then level up to 7500 for deeper, long-term transformation. Bundle them for the ultimate skincare journey.

        • Avoid direct contact with the eyes
        • Do not use if you are pregnant, nursing, or under 18
        • Keep out of reach of children
        • Patch testing is recommended and if redness or irritation occurs, discontinue use
        • If you have any preexisting conditions, consult your doctor before use

        We proudly ship helenor™ products worldwide, so no matter where you are, you can enjoy the benefits of our revolutionary skincare products.

        Of course! We want you to love your helenor exosome experience. If you’re not completely satisfied, you can return your order within 30 days of receiving it. Please ensure the product is unused and in its original packaging. Simply reach out to our customer support team, and we’ll guide you through the hassle-free return process.

        No, you do not have to pay any import duties and tax. We aim to provide a hassle-free shopping experience, so the price you see is the price you pay. There are no hidden fees or additional charges at delivery. This ensures that you can enjoy our products without worrying about extra costs.

        You can track your order by entering your order number and the email you used for your purchase here.

        4.7
        Rated 4.7 out of 5 stars
        Based on 1,632 reviews
        Total 5 star reviews: 1.3k Total 4 star reviews: 184 Total 3 star reviews: 64 Total 2 star reviews: 8 Total 1 star reviews: 33
        Slide 1 selected
        Write a Review (Opens in a new window)
        1,632 reviews
        • Diane M.
          Verified Buyer
          Reviewing
          Helenor ExoPlus® Serum Duo (2000+7500)
          I recommend this product
          Age range Over 60
          Rated 5 out of 5 stars
          Skeptical at first but wrong!

          I am halfway through my first bottle and I have to say, I see a difference in the intensity of my forehead lines! I bought this product on a recommendation but wasn’t honestly expecting any noticeable results, as been the case with most other products. But I’m pleased to say this one from Helenor is different in a really good way! The price point is also right, which is a huge plus in the facial care/serum space. I will be keeping this product in my face care regimen for sure.

          Was this helpful?
        • Virgil P.
          Verified Buyer
          Reviewing
          Helenor ExoPlus® Serum Duo (2000+7500)
          I recommend this product
          Age range 45-60
          Rated 5 out of 5 stars
          I wasn't sure at first

          I wasn’t sure how it was gonna work at first, but I feel like it is making my skin more youthful

          Was this helpful?
        • Molly P.
          Verified Buyer
          Reviewing
          Helenor ExoPlus® Serum Duo (2000+7500)
          I recommend this product
          Age range 45-60
          Rated 5 out of 5 stars
          Just beautiful results

          Very easy to use. Directions are clear. Results are amazing. Fine lines were gone after first use. Skin is firmer and clearer. I will use this product forever

          Was this helpful?
        • Ann M.
          Verified Buyer
          Reviewing
          Helenor ExoPlus® Serum Duo (2000+7500)
          I recommend this product
          Age range 45-60
          Rated 5 out of 5 stars
          Obsessed with this

          Obsessed with this! My pores are smaller, my skin is smoother, and I actually glow. The strong one is no joke, but the mild is perfect for daily use. No irritation, just results. Buying again!

          Was this helpful?
          Helenor
          6 months ago

          Obsessed with your results too! 😍✨ So glad you found your perfect combo; mild for daily glow, strong for extra boost! 💪💧 Can’t wait to pack your next order! 🛍️💕

        • Judith
          Verified Buyer
          Reviewing
          Helenor ExoPlus® Serum Mild (2000)
          I recommend this product
          Age range Over 60
          Rated 5 out of 5 stars
          Perfect

          Perfect

          Was this helpful?
        • Phoebe W.
          Verified Buyer
          Reviewing
          Helenor ExoPlus® Serum Duo (2000+7500)
          I recommend this product
          Age range 35-44
          Rated 5 out of 5 stars
          The science behind it is why I ordered.

          I am on my second bottle of this and can't say enough good things about it. The science behind it is why I ordered. My fine lines have significantly decreased and my skin overall just appears firmer. Will continue to purchase. It is a little pricey but considering all the benefits I believe its worth the price!

          Was this helpful?
        • Renee B.
          Verified Buyer
          Reviewing
          Helenor ExoPlus® Serum Strong (7500)
          I recommend this product
          Age range 45-60
          Rated 5 out of 5 stars
          Strong Works Better

          Great product. But the stronger one is 100% the way to go

          Was this helpful?